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KMID : 1035620130010010041
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Allergy Asthma & Respiratory Disease
2013 Volume.1 No. 1 p.41 ~ p.49
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Sensitization rates to inhalant allergens in children and adolescents of Incheon and Asan area and the relationship between polysensitization and prevalence of allergic diseases
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Kim Hyung-Young
Seo Ju-Hee
Jeong Young-Ho
Lee Eun
Yang Song-I
Ha Mi-Na
Kwon Ho-Jang
Leem Jong-Han
Kim Hwan-Cheol
Lee Kee-Jae
Park In-Ho
Lim Young-Wook
Lee Jong-Hyeon
Kim Ye-Ni
Choi Youn-Hee
Yu Jee-Suk
Kim Jeong-Seon
Yu Seung-Do
Lee Bo-Eun
Hong Se-hoon
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Abstract
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Purpose: Sensitization to allergens is considered as major mechanism of allergy and related to the development of allergic diseases. The objective of this study was to evaluate overall sensitization rates of inhalant allergens and the relationship between polysensitization and prevalence of allergic diseases in children and adolescents.
Methods: A cross-sectional pilot study of 122 elementary school students, 114 middle school students, and 115 high school students from Incheon and Asan was conducted by using the International Study of Asthma and Allergies in Childhood (ISSAC) questionnaire. The skin prick tests were performed with 14 common inhalant allergens on 339 students.
Results: The inhalant allergen that has a significantly different sensitization rate according to age was Dermatophagoides farinae. And the inhalant allergen that has significantly different sensitization rate according to region was Japanese hop. In addition, girls have higher sensitization rate to any mold allergens than boys. In case of having sensitization more than two allergens, the risks of diagnosis of asthma and allergic rhinitis on questionnaire were increased. Asthma is related to sensitization of dog or cat and allergic rhinitis is related to sensitization of house dust mites. However, atopic dermatitis is not related to sensitization of any inhalant allergens.
Conclusion: The sensitization rates of inhalant allergens may differ among age, gender, and region in children and adolescents of Incheon and Asan area. The polysensitized children and adolescents with inhalant allergens showed higher prevalences of allergic diseases such as asthma and allergic rhinitis on questionnaire than monosensitized group.
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KEYWORD
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Inhalant allergens, Skin prick test, Sensitization, PolysensitizationPurpose
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